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Anti-Mouse CFB Polyclonal Antibody (MF634014)

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Overview
Catalog No.MF634014
Description
Anti-Mouse CFB Polyclonal Antibody (MF634014) is a rabbit polyclonal antibody detecting Cfb. Suitable for Mouse.
Species reactivityMouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Mouse CFB (Gly484-Leu761).
Target Bf, C3/C5 convertase, Cfb, Complement factor B, Complement factor B Ba, Complement factor B Bb, EC:3.4.21.47, H2-Bf
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession P04186
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Complement factor B (CFB) is a ~85 kDa protein. Precursor of the catalytic component of the C3 and C5 convertase complexes of the alternative pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. The alternative complement pathway acts as an amplification loop that enhances other complement pathways (classical, lectin and GZMK) by promoting formation of additional C3 and C5 convertases. CFB is cleaved and activated by CFD to generate Ba and Bb chains; Bb chain constituting the catalytic component of the C3 and C5 convertases.

Note For research use only
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Formula
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Anti-Mouse CFB Polyclonal Antibody

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