

| Catalog No. | MB999014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Mouse PRDX6 Polyclonal Antibody (MB999014) is a rabbit polyclonal antibody detecting Prdx6. Suitable for Rat and Mouse.
Highlights
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| Species reactivity | Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Mouse PRDX6 (Met1-Pro224). | ||||||||
| Target | 1-Cys PRX, 1-Cys peroxiredoxin, Acidic calcium-independent phospholipase A2, Antioxidant protein 2, Aop2, EC:1.11.1.27, EC:2.3.1.23, EC:3.1.1.4, Glutathione-dependent peroxiredoxin, LPC acyltransferase 5, LPCAT-5, Ltw4, Lyso-PC acyltransferase 5, Lysophosphatidylcholine acyltransferase 5, NSGPx, Non-selenium glutathione peroxidase, Peroxiredoxin-6, Prdx5, Prdx6, aiPLA2 | ||||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | O08709 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Background | Peroxiredoxin-6 (PRDX6) is a ~24 kDa protein. Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. Has phospholipase activity. Can either reduce the oxidized sn-2 fatty acyl group of phospholipids (peroxidase activity) or hydrolyze the sn-2 ester bond of phospholipids (phospholipase activity). These activities are dependent on binding to phospholipids at acidic pH and to oxidized phospholipds at cytosolic pH. 1. Fisher, AB. et al. (2016) Journal of lipid research 57, 587-96. PMID: 26830860 | ||||||||
| Note | For research use only |

Western blot analysis was performed using anti-PRDX6 polyclonal antibody at 1ug/mL on various samples.
Lane 1: K562 cell lysate
Lane 2: Mouse brain lysate
Lane 3: Mouse liver lysate
Lane 4: Mouse spleen lysate
Lane 5: Rat brain lysate
Lane 6: Rat liver lysate
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