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Anti-Mouse LGALS8 Polyclonal Antibody (MT448014)

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Overview
Catalog No.MT448014
Description
Anti-Mouse LGALS8 Polyclonal Antibody (MT448014) is a rabbit polyclonal antibody detecting LGALS8. Suitable for Mouse.
Species reactivityMouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Mouse LGALS8 (Met1-Ala163).
Target Gal-8, Galectin-8, LGALS8, PCTA-1, Po66 carbohydrate-binding protein, Po66-CBP, Prostate carcinoma tumor antigen 1
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q9JL15
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Galectin-8 (LGALS8) is a ~36 kDa protein. Beta-galactoside-binding lectin that acts as a sensor of membrane damage caused by infection and restricts the proliferation of infecting pathogens by targeting them for autophagy. Detects membrane rupture by binding beta-galactoside ligands located on the lumenal side of the endosome membrane; these ligands becoming exposed to the cytoplasm following rupture. Restricts infection by initiating autophagy via interaction with CALCOCO2/NDP52. Required to restrict infection of bacterial invasion such as S.typhimurium. Also required to restrict infection of Picornaviridae viruses.

Note For research use only
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Anti-Mouse LGALS8 Polyclonal Antibody

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