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Anti-Human ACD Polyclonal Antibody (HP465014)

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Overview
Catalog No.HP465014
Description
Anti-Human ACD Polyclonal Antibody (HP465014) is a rabbit polyclonal antibody detecting ACD. Suitable for Human.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human ACD (Ser24-Glu196).
Target ACD, Adrenocortical dysplasia protein homolog, PIP1, POT1 and TIN2-interacting protein, PTOP, TINT1, TPP1
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q96AP0
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Adrenocortical dysplasia protein homolog (ACD) is a ~48 kDa protein. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends. Without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Promotes binding of POT1 to single-stranded telomeric DNA. Modulates the inhibitory effects of POT1 on telomere elongation.

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Anti-Human ACD Polyclonal Antibody

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