

| Catalog No. | MD460014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Mouse DYNC2I2 Polyclonal Antibody (MD460014) is a rabbit polyclonal antibody detecting DYNC2I2. Suitable for Mouse.
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| Species reactivity | Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Mouse DYNC2I2 (Val147-Thr537). | ||||||||
| Target | Cytoplasmic dynein 2 intermediate chain 2, DYNC2I2, Dynein 2 intermediate chain 2, WD repeat-containing protein 34, WDR34 | ||||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q5U4F6 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Background | Cytoplasmic dynein 2 intermediate chain 2 (DYNC2I2) is a ~58 kDa protein. Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 2 complex (dynein-2 complex), a motor protein complex that drives the movement of cargos along microtubules within cilia and flagella in concert with the intraflagellar transport (IFT) system. DYNC2I2 plays a major role in retrograde ciliary protein trafficking and in ciliogenesis. Required also to maintain a functional transition zone. 1. Wu, C. et al. (2017) Human molecular genetics 26, 2386-2397. PMID: 28379358 | ||||||||
| Note | For research use only |
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