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Anti-Mouse DYNC2I2 Polyclonal Antibody (MD460014)

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Overview
Catalog No.MD460014
Description
Anti-Mouse DYNC2I2 Polyclonal Antibody (MD460014) is a rabbit polyclonal antibody detecting DYNC2I2. Suitable for Mouse.
Species reactivityMouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Mouse DYNC2I2 (Val147-Thr537).
Target Cytoplasmic dynein 2 intermediate chain 2, DYNC2I2, Dynein 2 intermediate chain 2, WD repeat-containing protein 34, WDR34
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q5U4F6
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Cytoplasmic dynein 2 intermediate chain 2 (DYNC2I2) is a ~58 kDa protein. Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 2 complex (dynein-2 complex), a motor protein complex that drives the movement of cargos along microtubules within cilia and flagella in concert with the intraflagellar transport (IFT) system. DYNC2I2 plays a major role in retrograde ciliary protein trafficking and in ciliogenesis. Required also to maintain a functional transition zone.

1. Wu, C. et al. (2017) Human molecular genetics 26, 2386-2397. PMID: 28379358
Note For research use only
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
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