

| Catalog No. | HC916014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human CHML Polyclonal Antibody (HC916014) is a rabbit polyclonal antibody detecting CHML. Suitable for Human.
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| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human CHML (Arg216-Ile600). | ||||||||
| Target | CHML, Choroideremia-like protein, REP-2, REP2, Rab escort protein 2, Rab proteins geranylgeranyltransferase component A 2 | ||||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P26374 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Background | Rab proteins geranylgeranyltransferase component A 2 (CHML) is a ~74 kDa protein. Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Less effective than CHM in supporting prenylation of Rab3 family. | ||||||||
| Note | For research use only |
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