

| Catalog No. | MC339014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Mouse CDw210b/IL10RB Polyclonal Antibody (MC339014) is a rabbit polyclonal antibody detecting CDw210b. Suitable for Mouse.
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| Species reactivity | Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Mouse CDw210b/IL10RB (Met20-Asn214). | ||||||||
| Tested applications | WB | ||||||||
| Target | CDw210b, CRF2-4, CRFB4, Cytokine receptor class-II member 4, Cytokine receptor family 2 member 4, D21S58, D21S66, IL-10 receptor subunit beta, IL-10R subunit 2, IL-10R subunit beta, IL-10R2, IL-10RB, IL10RB, Interleukin-10 receptor subunit 2, Interleukin-10 receptor subunit beta | ||||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q61190 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Background | Interleukin-10 receptor subunit beta (CDw210b/IL10RB) is a ~39 kDa protein. Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state. | ||||||||
| Note | For research use only |

Western blot analysis was performed using anti-IL10RB polyclonal antibody at 1ug/mL on various samples.
Lane 1: Rat heart lysate




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