Anti-Oleclumab Neutralizing Recombinant Antibody (SAA2939) (AB209013)

Name: Anti-Oleclumab Neutralizing Recombinant Antibody (SAA2939)
Brand: abinScience
SKU: AB209013
Price: 168 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

AB209013

Description

Anti-Oleclumab Neutralizing Recombinant Antibody (SAA2939) (AB209013) is a mouse monoclonal antibody detecting Oleclumab in ELISA. Suitable for General.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.

Species reactivity

General

Applications

ELISA

Host species

Mouse

Clonality

Monoclonal

Isotype

IgG1, kappa

Clone ID

SAA2939

Expression system

Mammalian cells

Immunogen

Oleclumab

Target

Oleclumab

Endotoxin level

< 10 EU/mg as determined by LAL method.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

CAS: 1803176-05-7

Form

Liquid

Storage buffer

0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

5'-nucleotidase (Oleclumab) is a ~63 kDa protein. Catalyzes the hydrolysis of nucleotide monophosphates, releasing inorganic phosphate and the corresponding nucleoside, with AMP being the preferred substrate. Shows a preference for ribonucleotide monophosphates over their equivalent deoxyribose forms. Other substrates include IMP, UMP, GMP, CMP, dAMP, dCMP, dTMP, NAD and NMN.

1. Garavaglia, S. et al. (2012) The Biochemical journal 441, 131-41. PMID: 21933152

2. Heuts, DP. et al. (2012) Chembiochem : a European journal of chemical biology 13, 2384-91. PMID: 22997138

3. Knapp, K. et al. (2012) Structure (London, England : 1993) 20, 2161-73. PMID: 23142347

4. Fausther, M. et al. (2014) PloS one 9, e98568. PMID: 24887587

5. Scaletti, E. et al. (2021) Purinergic signalling 17, 693-704. PMID: 34403084

Note

For research use only.

Images

Bioactivity

Detects Oleclumab in indirect ELISA.
Bioactivity

Blocks the binding of Oleclumab to CD73.

References

Datasheet

Anti-Oleclumab Neutralizing Recombinant Antibody (SAA2939).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Oleclumab Neutralizing Recombinant Antibody (SAA2939) (AB209013)

Overview

Images

References

Datasheet

SDS