Anti-Ibalizumab Neutralizing Recombinant Antibody (SAA2976) (AF998023)

Name: Anti-Ibalizumab Neutralizing Recombinant Antibody (SAA2976)
Brand: abinScience
SKU: AF998023
Price: 168 USD
Availability: InStock

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Datasheet
SDS

Overview

Catalog No.	AF998023
Description	Anti-Ibalizumab Neutralizing Recombinant Antibody (SAA2976) (AF998023) is a mouse monoclonal antibody detecting Ibalizumab in ELISA. Suitable for General. Highlights ●Affinity Purified — Minimal background and high purity for reliable results.
Species reactivity	General
Applications	ELISA
Host species	Mouse
Clonality	Monoclonal
Isotype	IgG1
Clone ID	SAA2976
Expression system	Mammalian cells
Immunogen	Ibalizumab
Endotoxin level	< 10 EU/mg as determined by LAL method.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	CAS: 680188-33-4
Form	Liquid
Storage buffer	0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	T-cell surface glycoprotein CD4 (Ibalizumab) is a ~51 kDa protein. Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex.
Note	For research use only.

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Bioactivity

Detects Ibalizumab in indirect ELISA.
Bioactivity

Blocks the binding of Ibalizumab to CD4.

References

Datasheet

Anti-Ibalizumab Neutralizing Recombinant Antibody (SAA2976).pdf

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Formula

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Recombinant Proteins

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Anti-Ibalizumab Neutralizing Recombinant Antibody (SAA2976) (AF998023)

Overview

Images

References

Datasheet

SDS