Anti-Human Flt-3/Flk-2 Recombinant Nanobody, C-Sortase tag (SAA1328) (HW794023)

Name: Anti-Human Flt-3/Flk-2 Recombinant Nanobody, C-Sortase tag (SAA1328)
Brand: abinScience
SKU: HW794023
Price: 191 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HW794023

Description

Anti-Human Flt-3/Flk-2 Recombinant Nanobody, C-Sortase tag (SAA1328) (HW794023) is a alpaca monoclonal antibody detecting Flt-3/Flk-2 in ELISA, FCM. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human

Applications

ELISA, FCM

Host species

Alpaca

Clonality

Monoclonal

Isotype

VHH-Sortase Tag-6His

Clone ID

SAA1328

Target

CD135, EC:2.7.10.1, FL cytokine receptor, FLK-2, FLK2, FLT-3, FLT3, Fetal liver kinase-2, Fms-like tyrosine kinase 3, Receptor-type tyrosine-protein kinase FLT3, STK-1, STK1, Stem cell tyrosine kinase 1

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Purified by Nickel column

Accession

P36888

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Receptor-type tyrosine-protein kinase FLT3 (CD135) is a ~112 kDa protein. Tyrosine-protein kinase that acts as a cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 and AKT1, and activation of the downstream effector MTOR. Promotes activation of RAS signaling and phosphorylation of downstream kinases, including MAPK1/ERK2 and/or MAPK3/ERK1. Promotes phosphorylation of FES, FER, PTPN6/SHP, PTPN11/SHP-2, PLCG1, and STAT5A and/or STAT5B. Activation of wild-type FLT3 causes only marginal activation of STAT5A or STAT5B.

Note

For research use only

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