

| Catalog No. | MY280014 | ||||||
|---|---|---|---|---|---|---|---|
| Description |
Anti-Mouse CCL2/MCP-1 Polyclonal Antibody (MY280014) is a rabbit polyclonal antibody detecting CCL2/MCP-1 in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| Species reactivity | Mouse | ||||||
| Applications | ELISA, IHC, WB | ||||||
| Host species | Rabbit | ||||||
| Clonality | Polyclonal | ||||||
| Isotype | IgG | ||||||
| Immunogen | E. coli - derived recombinant Mouse CCL2/MCP-2 (Gln24-Arg96). | ||||||
| Target | C-C motif chemokine 2, Ccl2, Je, MCP-1, Mcp1, Monocyte chemoattractant protein 1, Monocyte chemotactic protein 1, Platelet-derived growth factor-inducible protein JE, Scya2, Small-inducible cytokine A2 | ||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||
| Observed Molecular Weight | 20 kDa | ||||||
| Purification | Purified by antigen affinity column. | ||||||
| Accession | P10148 | ||||||
| Form | Liquid | ||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. | ||||||
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. | ||||||
| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||
| Background | C-C motif chemokine 2 (HC11,MCP-1,MCP1,Monocyte chemotactic protein 1,Monocyte chemotactic and activating factor,Small-inducible cytokine A2,SCYA2,MCAF,Monocyte secretory protein JE,C-C motif chemokine 2,Monocyte chemoattractant protein 1,CCL2) is a ~11 kDa protein. Acts as a ligand for C-C chemokine receptor CCR2. Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions. Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. 1. Hemmerich, S. et al. (1999) Biochemistry 38, 13013-25. PMID: 10529171 2. Jarnagin, K. et al. (1999) Biochemistry 38, 16167-77. PMID: 10587439 3. Paavola, CD. et al. (1998) The Journal of biological chemistry 273, 33157-65. PMID: 9837883 4. Zhang, YJ. et al. (1994) The Journal of biological chemistry 269, 15918-24. PMID: 8195247 5. Weber, M. et al. (1996) The Journal of experimental medicine 183, 681-5. PMID: 8627182 6. Chakravarty, L. et al. (1998) The Journal of biological chemistry 273, 29641-7. PMID: 9792674 7. Li, YS. et al. (1993) Molecular and cellular biochemistry 126, 61-8. PMID: 8107690 | ||||||
| Note | For research use only. |
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