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Anti-SFTSV Glycoprotein Gn Recombinant Nanobody (SAA3001) (VK662093)

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Overview
Catalog No.VK662093
Description
Anti-SFTSV Glycoprotein Gn Recombinant Nanobody (SAA3001) (VK662093) is a alpaca monoclonal antibody detecting Glycoprotein Gn in ELISA. Suitable for Dabie bandavirus (Severe fever with thrombocytopenia virus) (SFTSV) (Huaiyangshan banyangvirus).
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
Species reactivityDabie bandavirus (Severe fever with thrombocytopenia virus) (SFTSV) (Huaiyangshan banyangvirus)
ApplicationsELISA
Host speciesAlpaca
ClonalityMonoclonal
IsotypeVHH-His
Clone IDSAA3001
Target Glycoprotein N, Gn, Glycoprotein G1
Endotoxin level < 10 EU/mg as determined by LAL method.
Purity >95% as determined by SDS-PAGE.
Purification Purified by Nickel column.
Accession A0A0B5A886
Form Liquid
Storage buffer 0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:2000-1:20000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Envelopment polyprotein (Mgp1/membrane glycoprotein polyprotein) is a ~116 kDa protein. Structural component of the virion that interacts with glycoprotein C. It shields the hydrophobic fusion loops of the glycoprotein C, preventing premature fusion. The glycoprotein protrusions are arranged on an icosahedral lattice, with T=12 triangulation. They are able to attach the virion to the host cell receptor CD209/DC-SIGN and to promote fusion of membranes with the late endosome after clathrin-mediated endocytosis of the virion. Plays a role in the packaging of ribonucleoproteins during virus assembly.

1. Hofmann, H. et al. (2013) Journal of virology 87, 4384-94. PMID: 23388721
Note For research use only.
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-SFTSV Glycoprotein Gn Recombinant Nanobody (SAA3001)

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