Anti-Human CD180 Recombinant Antibody (ABB071) (HV191013)

Name: Anti-Human CD180 Recombinant Antibody (ABB071)
Brand: abinScience
SKU: HV191013
Price: 191 USD
Availability: InStock

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Overview

Catalog No.	HV191013
Description	Anti-Human CD180 Recombinant Antibody (ABB071) (HV191013) is a human monoclonal antibody detecting CD180 in ELISA, FCM, Functional assay. Suitable for Human. Highlights ●Affinity Purified — Minimal background and high purity for reliable results. ●Multi-Application — Validated across multiple applications.
Species reactivity	Human
Applications	ELISA, FCM, Functional assay
Host species	Human
Clonality	Monoclonal
Isotype	IgG1, kappa
Clone ID	ABB071
Target	CD180, CD180 antigen, LY64, Lymphocyte antigen 64, RP105, Radioprotective 105 kDa protein
Endotoxin level	< 10 EU/mg as determined by LAL method.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q99467
Form	Liquid
Storage buffer	0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	CD180 antigen is a ~74 kDa protein. Pattern recognition receptor predominantly expressed on B-cells, dendritic cells, and certain monocytes/macrophages, structurally resembling Toll-like receptors (TLRs) that plays a role in modulating immune responses. While ressembling a TLR, lacks the intracellular TIR (Toll/IL-1R) signaling domain and thus does not directly transduce signals. Instead, modulates immune responses, often in conjunction with other TLRs. For example, in cooperation with MD-1/LY86, interacts directly with the TLR4 signaling complex, inhibiting its ability to bind microbial ligand. 1. Divanovic, S. et al. (2005) Nature immunology 6, 571-8. PMID: 15852007
Note	For research use only.

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Datasheet

Anti-Human CD180 Recombinant Antibody (ABB071).pdf

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Anti-Human CD180 Recombinant Antibody (ABB071) (HV191013)

Overview

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References

Datasheet

SDS