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Anti-Mouse IRF9 Polyclonal Antibody (MX843014)

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Overview
Catalog No.MX843014
Description
Anti-Mouse IRF9 Polyclonal Antibody (MX843014) is a rabbit polyclonal antibody detecting IRF9 in ELISA, IHC, WB. Suitable for Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Species reactivityMouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
ClonalityPolyclonal
IsotypeIgG
Immunogen E. coli - derived recombinant Mouse IRF9 (Asp211-His399).
Target IFN-alpha-responsive transcription factor subunit, IRF-9, IRF9, ISGF-3 gamma, ISGF3 p48 subunit, ISGF3G, Interferon regulatory factor 9, Interferon-stimulated gene factor 3 gamma, Transcriptional regulator ISGF3 subunit gamma
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q61179
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Interferon regulatory factor 9 (IRF9) is a ~43 kDa protein. Transcription factor that plays an essential role in anti-viral immunity. It mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. IRF9/ISGF3G associates with the phosphorylated STAT1:STAT2 dimer to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.

Note For research use only
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Formula
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Anti-Mouse IRF9 Polyclonal Antibody

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