

| Catalog No. | MV971014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Mouse NUMBL Polyclonal Antibody (MV971014) is a rabbit polyclonal antibody detecting NUMBL in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
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| Species reactivity | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Clonality | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogen | E. coli - derived recombinant Mouse NUMBL (Ser61-Cys206). | ||||||||
| Target | NUMBL, Numb-R, Numb-like protein, Numb-related protein | ||||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | O08919 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Background | Numb-like protein (NUMBL) is a ~64 kDa protein. Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of embryonic neurogenesis. Also required postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. Negative regulator of NF-kappa-B signaling pathway. | ||||||||
| Note | For research use only |
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