Anti-African clawed frog IRF7 Polyclonal Antibody (ZD620014)

Name: Anti-African clawed frog IRF7 Polyclonal Antibody
Brand: abinScience
SKU: ZD620014
Price: 168 USD
Availability: InStock

Datasheet Share product Copy info

Price(USD): --

Spec:

50ug
100ug

Number:

Get quote

Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

ZD620014

Description

Anti-African clawed frog IRF7 Polyclonal Antibody (ZD620014) is a rabbit polyclonal antibody detecting IRF7 in ELISA, IHC, WB. Suitable for Xenopus laevis (African clawed frog).

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Xenopus laevis (African clawed frog)

Applications

ELISA, IHC, WB

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Immunogen

E. coli - derived recombinant African clawed frog IRF7 (Met1-Pro127).

Target

IRF-7, IRF7, Interferon regulatory factor 7

Endotoxin level

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Accession

A0A1L8GJP7

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Background

Interferon regulatory factor 7 is a ~54 kDa protein. Key transcriptional regulator of type I interferon (IFN)-dependent immune responses and plays a critical role in the innate immune response against DNA and RNA viruses. Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters. Can efficiently activate both the IFN-beta (IFNB) and the IFN-alpha (IFNA) genes and mediate their induction via both the virus-activated, MyD88-independent pathway and the TLR-activated, MyD88-dependent pathway. Induces transcription of ubiquitin hydrolase USP25 mRNA in response to lipopolysaccharide (LPS) or viral infection in a type I IFN-dependent manner. Required during both the early and late phases of the IFN gene induction but is more critical for the late than for the early phase.

1. Hwang, SW. et al. (2017) Biochemical and biophysical research communications 486, 700-705. PMID: 28342865

2. Kitagawa, Y. et al. (2017) Journal of virology 91. PMID: 28768858

3. Panne, D. et al. (2007) Cell 129, 1111-23. PMID: 17574024

4. Zhang, Q. et al. (2020) Science (New York, N.Y.) 370. PMID: 32972995

5. Marié, I. et al. (2000) Molecular and cellular biology 20, 8803-14. PMID: 11073981

6. Caillaud, A. et al. (2002) The Journal of biological chemistry 277, 49417-21. PMID: 12374802

7. Kawai, T. et al. (2004) Nature immunology 5, 1061-8. PMID: 15361868

8. Sgarbanti, M. et al. (2007) Annals of the New York Academy of Sciences 1095, 325-33. PMID: 17404045

Note

For research use only

Images

References

Datasheet

Anti-African clawed frog IRF7 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-African clawed frog IRF7 Polyclonal Antibody (ZD620014)

Overview

Images

References

Datasheet

SDS