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Anti-Retatrutide Polyclonal Antibody (HW328024)

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Overview
Catalog No.HW328024
Description
Anti-Retatrutide Polyclonal Antibody (HW328024) is a rabbit polyclonal antibody detecting GLP-1R in ELISA, IHC, WB. Suitable for General.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Species reactivityGeneral
ApplicationsELISA
Host speciesRabbit
ClonalityPolyclonal
IsotypeIgG
Immunogen Retarutide
Target Retarutide
Specificity The product is specific for Retarutide. This antibody serves as an excellent positive control for Retarutide immunogenicity (ADA) assays.
Endotoxin level Please contact with the lab for this information.
Purity >90% as determined by SDS-PAGE.
Purification Purified by antigen affinity column.
Accession CAS: 2381089-83-2
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Glucagon-like peptide 1 receptor (GLP1R) is a ~53 kDa protein. G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a role in regulating insulin secretion in response to GLP-1.

1. Underwood, CR. et al. (2010) The Journal of biological chemistry 285, 723-30. PMID: 19861722
2. Lau, J. et al. (2015) Journal of medicinal chemistry 58, 7370-80. PMID: 26308095
3. Hennen, S. et al. (2016) Scientific reports 6, 26236. PMID: 27196125
4. Song, G. et al. (2017) Nature 546, 312-315. PMID: 28514449
5. van Eyll, B. et al. (1994) FEBS letters 348, 7-13. PMID: 7517895
6. Graziano, MP. et al. (1993) Biochemical and biophysical research communications 196, 141-6. PMID: 8216285
7. Thorens, B. et al. (1993) Diabetes 42, 1678-82. PMID: 8405712
Note For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
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Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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