Anti-Human IL-23R Recombinant Antibody (Schering patent anti-IL-23R) (HV464043)

Name: Anti-Human IL-23R Recombinant Antibody (Schering patent anti-IL-23R)
Brand: abinScience
SKU: HV464043
Price: 191 USD
Availability: InStock

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100ug
1mg

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HV464043

Description

Anti-Human IL-23R Recombinant Antibody (Schering patent anti-IL-23R) (HV464043) is a human monoclonal antibody detecting IL-23R in ELISA, FCM. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human

Applications

ELISA, FCM

Host species

Human

Clonality

Monoclonal

Isotype

IgG1, kappa

Clone ID

Schering patent anti-IL-23R

Tested applications

FCM

Target

IL-23 receptor, IL-23R, IL23R, Interleukin-23 receptor

Endotoxin level

< 10 EU/mg as determined by LAL method.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q5VWK5

Form

Liquid

Storage buffer

0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Interleukin-23 receptor (IL23R) is a ~73 kDa protein. Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis.

Note

For research use only.

Images

Flow cytometry

Flow-cytometry using anti-human IL-23R antibody. HEK293 Transtected cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human IL-23R monoclonal antibody (Catalog HV464043, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.

References

Datasheet

Anti-Human IL-23R Recombinant Antibody (Schering patent anti-IL-23R).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human IL-23R Recombinant Antibody (Schering patent anti-IL-23R) (HV464043)

Overview

Images

References

Datasheet

SDS