

| Catalog No. | HV780023 | ||||
|---|---|---|---|---|---|
| Description |
Anti-Human DKK2 Recombinant Antibody (M-751) (HV780023) is a human monoclonal antibody detecting DKK2 in ELISA. Suitable for Human.
Highlights
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| Species reactivity | Human | ||||
| Applications | ELISA | ||||
| Host species | Human | ||||
| Clonality | Monoclonal | ||||
| Isotype | IgG4, kappa | ||||
| Clone ID | M-751 | ||||
| Target | DKK2, Dickkopf-2, Dickkopf-related protein 2, Dkk-2, hDkk-2 | ||||
| Endotoxin level | < 10 EU/mg as determined by LAL method. | ||||
| Purity | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Accession | Q9UBU2 | ||||
| Form | Liquid | ||||
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Background | Dickkopf-related protein 2 (DKK2) is a ~28 kDa protein. Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. | ||||
| Note | For research use only. |



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