Anti-JCPyV VP1 Recombinant Antibody (SAA3058) (VK698013)

Name: Anti-JCPyV VP1 Recombinant Antibody (SAA3058)
Brand: abinScience
SKU: VK698013
Price: 191 USD
Availability: InStock

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100ug
1mg

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

VK698013

Description

Anti-JCPyV Major capsid protein VP1 Recombinant Antibody (SAA3058) (VK698013) is a human monoclonal antibody detecting Major capsid protein VP1 in ELISA, Neutralizing, Blocking. Suitable for JC polyomavirus (JCPyV/JCV), BK polyomavirus (BKPyV).

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

JC polyomavirus (JCPyV/JCV), BK polyomavirus (BKPyV)

Applications

ELISA, Neutralizing, Blocking

Host species

Human

Clonality

Monoclonal

Isotype

IgG

Clone ID

SAA3058

Target

Major capsid protein VP1, Major structural protein VP1

Endotoxin level

< 10 EU/mg as determined by LAL method.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P03089, P03088

Form

Liquid

Storage buffer

0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Major capsid protein VP1 is a ~40 kDa protein. Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with VP2 or VP3 proteins. Interacts with gangliosides GT1b and GD1b containing terminal alpha(2-8)-linked sialic acids on the cell surface to provide virion attachment to target cell. This attachment induces virion internalization predominantly through caveolin-mediated endocytosis and traffics to the endoplasmic reticulum. Inside the endoplasmic reticulum, the protein folding machinery isomerizes VP1 interpentamer disulfide bonds, thereby triggering initial uncoating.

Note

For research use only.

Images

References

Datasheet

Anti-JCPyV VP1 Recombinant Antibody (SAA3058).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-JCPyV VP1 Recombinant Antibody (SAA3058) (VK698013)

Overview

Images

References

Datasheet

SDS