

| Catalog No. | HV126023 | ||||
|---|---|---|---|---|---|
| Description |
Anti-Human LILRB4/CD85k/ILT3 Recombinant Antibody (SAA3061) (HV126023) is a human monoclonal antibody detecting LILRB4/CD85k/ILT3 in ELISA, FCM. Suitable for Human.
Highlights
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| Species reactivity | Human | ||||
| Applications | ELISA, FCM | ||||
| Host species | Human | ||||
| Clonality | Monoclonal | ||||
| Isotype | IgG1, kappa | ||||
| Clone ID | SAA3061 | ||||
| Target | B4, CD85 antigen-like family member K, CD85k, ILT-3, ILT3, Immunoglobulin-like transcript 3, LILRB4, LIR-5, LIR5, Leukocyte immunoglobulin-like receptor 5, Leukocyte immunoglobulin-like receptor subfamily B member 4, Monocyte inhibitory receptor HM18 | ||||
| Endotoxin level | Please contact with the lab for this information. | ||||
| Purity | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Accession | Q8NHJ6 | ||||
| Form | Liquid | ||||
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. | ||||
| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Background | Leukocyte immunoglobulin-like receptor subfamily B member 4 (CD85k/LILRB4) is a ~49 kDa protein. Inhibitory receptor involved in the down-regulation of the immune response and the development of immune tolerance. Receptor for FN1. Receptor for apolipoprotein APOE. Receptor for ALCAM/CD166. Inhibits receptor-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions. 1. Chang, CC. et al. (2002) Nature immunology 3, 237-43. PMID: 11875462 2. Su, MT. et al. (2021) International immunology 33, 447-458. PMID: 34089617 3. Deng, M. et al. (2018) Nature 562, 605-609. PMID: 30333625 4. Xu, Z. et al. (2018) Journal of immunology (Baltimore, Md. : 1950) 200, 1207-1219. PMID: 29263213 5. Cella, M. et al. (1997) The Journal of experimental medicine 185, 1743-51. PMID: 9151699 6. Lu, HK. et al. (2009) The Journal of biological chemistry 284, 34839-48. PMID: 19833736 7. Kim-Schulze, S. et al. (2006) Journal of immunology (Baltimore, Md. : 1950) 176, 2790-8. PMID: 16493035 | ||||
| Note | For research use only |




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