Anti-Human SLC16A1/MCT1 Recombinant Antibody (Immunometabolism patent anti-MCT1) (HX905023)

Name: Anti-Human SLC16A1/MCT1 Recombinant Antibody (Immunometabolism patent anti-MCT1)
Brand: abinScience
SKU: HX905023
Price: 191 USD
Availability: InStock

Datasheet Share product Copy info

Price(USD):

Spec:

50ug
100ug
1mg

Number:

Get quote

Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HX905023

Description

Anti-Human SLC16A1/MCT1 Recombinant Antibody (Immunometabolism patent anti-MCT1) (HX905023) is a human monoclonal antibody detecting SLC16A1/MCT1 in ELISA. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.

Species reactivity

Human

Applications

ELISA

Host species

Human

Clonality

Monoclonal

Isotype

IgG1, kappa

Clone ID

Immunometabolism patent anti-MCT1

Target

MCT 1, MCT1, Monocarboxylate transporter 1, SLC16A1, Solute carrier family 16 member 1

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P53985

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Monocarboxylate transporter 1 (SLC16A1/MCT1) is a ~53 kDa protein. Bidirectional proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, acetate and the ketone bodies acetoacetate and beta-hydroxybutyrate, and thus contributes to the maintenance of intracellular pH. The transport direction is determined by the proton motive force and the concentration gradient of the substrate monocarboxylate. MCT1 is a major lactate exporter. Plays a role in cellular responses to a high-fat diet by modulating the cellular levels of lactate and pyruvate that contribute to the regulation of central metabolic pathways and insulin secretion, with concomitant effects on plasma insulin levels and blood glucose homeostasis.

1. Pullen, TJ. et al. (2012) Diabetes 61, 1719-25. PMID: 22522610

2. Lengacher, S. et al. (2013) PloS one 8, e82505. PMID: 24367518

3. Reddy, A. et al. (2020) Cell 183, 62-75.e17. PMID: 32946811

Note

For research use only

Images

References

Datasheet

Anti-Human SLC16A1/MCT1 Recombinant Antibody (Immunometabolism patent anti-MCT1).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human SLC16A1/MCT1 Recombinant Antibody (Immunometabolism patent anti-MCT1) (HX905023)

Overview

Images

References

Datasheet

SDS

Quick access

Contact Us