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Anti-Human IL-12 R beta 1 Recombinant Antibody (Novartis patent anti-IL-12Rβ1) (HW512023)

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Overview
Catalog No.HW512023
Description
Anti-Human IL-12 R beta 1 Recombinant Antibody (Novartis patent anti-IL-12Rβ1) (HW512023) is a human monoclonal antibody detecting IL-12 R beta 1 in ELISA. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
Species reactivityHuman
ApplicationsELISA
Host speciesHuman
ClonalityMonoclonal
IsotypeIgG1, kappa
Clone IDNovartis patent anti-IL-12Rβ1
Target CD212, IL-12 receptor beta component, IL-12 receptor subunit beta-1, IL-12R subunit beta-1, IL-12R-beta-1, IL-12RB1, IL12R, IL12RB, IL12RB1, Interleukin-12 receptor subunit beta-1
Endotoxin level < 10 EU/mg
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P42701
Form Liquid
Storage buffer 0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:2000-1:20000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Interleukin-12 receptor subunit beta-1 (CD212/IL12RB1) is a ~73 kDa protein. Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Also associates with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade.

Note For research use only
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Formula
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Formula
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