

| Catalog No. | HW512023 | ||||
|---|---|---|---|---|---|
| Description |
Anti-Human IL-12 R beta 1 Recombinant Antibody (Novartis patent anti-IL-12Rβ1) (HW512023) is a human monoclonal antibody detecting IL-12 R beta 1 in ELISA. Suitable for Human.
Highlights
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| Species reactivity | Human | ||||
| Applications | ELISA | ||||
| Host species | Human | ||||
| Clonality | Monoclonal | ||||
| Isotype | IgG1, kappa | ||||
| Clone ID | Novartis patent anti-IL-12Rβ1 | ||||
| Target | CD212, IL-12 receptor beta component, IL-12 receptor subunit beta-1, IL-12R subunit beta-1, IL-12R-beta-1, IL-12RB1, IL12R, IL12RB, IL12RB1, Interleukin-12 receptor subunit beta-1 | ||||
| Endotoxin level | < 10 EU/mg | ||||
| Purity | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Accession | P42701 | ||||
| Form | Liquid | ||||
| Storage buffer | 0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Background | Interleukin-12 receptor subunit beta-1 (CD212/IL12RB1) is a ~73 kDa protein. Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Also associates with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade. | ||||
| Note | For research use only |




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