Anti-Human IL-1Rrp2/IL-1R6 Reference Antibody (Relakimig, RUO) (HV045036)

Name: Anti-Human IL-1Rrp2/IL-1R6 Reference Antibody (Relakimig, RUO)
Brand: abinScience
SKU: HV045036
Price: 370 USD
Availability: InStock

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Overview

Catalog No.	HV045036
Description	Anti-Human IL-1Rrp2/IL-1R6 Reference Antibody (Relakimig, RUO) (HV045036) is a human monoclonal antibody detecting IL-1Rrp2/IL-1R6.
Species reactivity	Human
Applications	ELISA, FCM, Functional assay
Host species	Human
Clonality	Monoclonal
Isotype	immunoglobulin (VH-H-gamma1_L-kappa) dimer
Target	EC:3.2.2.6, IL-1Rrp2, IL-36 receptor, IL-36R, IL1R-rp2, IL1RL2, IL1RRP2, Interleukin-1 receptor-like 2, Interleukin-1 receptor-related protein 2, IL-23 subunit alpha, IL-23-A, IL-23p19, IL23A, Interleukin-23 subunit alpha, Interleukin-23 subunit p19, SGRF
Endotoxin level	< 10 EU/mg
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q9HB29 & Q9NPF7
Form	Liquid
Storage buffer	0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term from the date of receipt..
Alternate Names	CAS: 3081158-72-4
Background	Interleukin-1 receptor-like 2 (IL1RL2/IL-36R) is a ~65 kDa protein. Receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways. The IL-36 signaling system is thought to be present in epithelial barriers and to take part in local inflammatory response; it is similar to the IL-1 system. Seems to be involved in skin inflammatory response by induction of the IL-23/IL-17/IL-22 pathway.
Note	For research use only.

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Anti-Human IL-1Rrp2/IL-1R6 Reference Antibody (Relakimig, RUO).pdf

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Anti-Human IL-1Rrp2/IL-1R6 Reference Antibody (Relakimig, RUO) (HV045036)

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