Anti-Human TNF RII/TNFRSF1B Reference Antibody (Zimlekitug, RUO) (HB070096)

Name: Anti-Human TNF RII/TNFRSF1B Reference Antibody (Zimlekitug, RUO)
Brand: abinScience
SKU: HB070096
Price: 370 USD
Availability: InStock

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100ug
1mg

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Overview

Catalog No.	HB070096
Description	Anti-Human TNF RII/TNFRSF1B Reference Antibody (Zimlekitug, RUO) (HB070096) is a human monoclonal antibody detecting TNF RII/TNFRSF1B.
Species reactivity	Human
Applications	ELISA, FACS, Functional assay
Host species	Human
Clonality	Monoclonal
Isotype	IgG1, lambda2
Target	CD120b, Etanercept, TBP-2, TBPII, TNF-R2, TNF-RII, TNFBR, TNFR-II, TNFR2, TNFRSF1B, Tumor necrosis factor receptor 2, Tumor necrosis factor receptor superfamily member 1B, Tumor necrosis factor receptor superfamily member 1b, membrane form, Tumor necrosis factor receptor type II, Tumor necrosis factor-binding protein 2, p75, p80 TNF-alpha receptor
Endotoxin level	< 10 EU/mg
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P20333
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term from the date of receipt..
Alternate Names	CAS: 3079497-57-4
Background	Tumor necrosis factor receptor superfamily member 1B (CD120b/TNFR2) is a ~48 kDa protein. Receptor with high affinity for TNFSF2/TNF and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF. Isoform 2 blocks TNF-induced apoptosis, which suggests that it regulates TNF function by antagonizing its biological activity.
Note	For research use only.