

| Catalog No. | HC619014 | ||||||
|---|---|---|---|---|---|---|---|
| Description |
Anti-Human SMC1A Polyclonal Antibody (HC619014) is a rabbit polyclonal antibody detecting SMC1A in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
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| Species reactivity | Human, Mouse, Rat | ||||||
| Applications | ELISA, IHC, WB | ||||||
| Host species | Rabbit | ||||||
| Clonality | Polyclonal | ||||||
| Isotype | IgG | ||||||
| Immunogen | E. coli - derived recombinant Human SMC1A (Ile489-Asp667). | ||||||
| Target | DXS423E, KIAA0178, SB1.8, SMC protein 1A, SMC-1-alpha, SMC-1A, SMC1, SMC1A, SMC1L1, Sb1.8, Structural maintenance of chromosomes protein 1A | ||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||
| Purification | Purified by antigen affinity column. | ||||||
| Accession | Q14683 | ||||||
| Form | Liquid | ||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. | ||||||
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. | ||||||
| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||
| Background | Structural maintenance of chromosomes protein 1A (SMC1A) is a ~143 kDa protein. Involved in chromosome cohesion during cell cycle and in DNA repair. Central component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. | ||||||
| Note | For research use only. |
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