Anti-Human GLP-1R Recombinant Antibody (Gipg013) (HW328023)

Name: Anti-Human GLP-1R Recombinant Antibody (Gipg013)
Brand: abinScience
SKU: HW328023
Price: 191 USD
Availability: InStock

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50ug
100ug
1mg

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HW328023

Description

Anti-Human GLP-1R Recombinant Antibody (Gipg013) (HW328023) is a mouse monoclonal antibody detecting GLP-1R in ELISA, FCM. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human

Applications

ELISA, FCM

Host species

Mouse

Clonality

Monoclonal

Isotype

IgG1, kappa

Clone ID

Gipg013

Target

GIP-R, GIPR, Gastric inhibitory polypeptide receptor, Glucose-dependent insulinotropic polypeptide receptor

Endotoxin level

< 10 EU/mg as determined by LAL method.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P48546

Form

Liquid

Storage buffer

0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Glucagon-like peptide 1 receptor (GLP1R) is a ~53 kDa protein. G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a role in regulating insulin secretion in response to GLP-1.

1. Underwood, CR. et al. (2010) The Journal of biological chemistry 285, 723-30. PMID: 19861722

2. Lau, J. et al. (2015) Journal of medicinal chemistry 58, 7370-80. PMID: 26308095

3. Hennen, S. et al. (2016) Scientific reports 6, 26236. PMID: 27196125

4. Song, G. et al. (2017) Nature 546, 312-315. PMID: 28514449

5. van Eyll, B. et al. (1994) FEBS letters 348, 7-13. PMID: 7517895

6. Graziano, MP. et al. (1993) Biochemical and biophysical research communications 196, 141-6. PMID: 8216285

7. Thorens, B. et al. (1993) Diabetes 42, 1678-82. PMID: 8405712

Note

For research use only.

Images

References

Datasheet

Anti-Human GLP-1R Recombinant Antibody (Gipg013).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human GLP-1R Recombinant Antibody (Gipg013) (HW328023)

Overview

Images

References

Datasheet

SDS