

| Catalog No. | HS742023 | ||||
|---|---|---|---|---|---|
| Description |
Anti-Human ABCB5 Recombinant Antibody (SAA3086) (HS742023) is a human monoclonal antibody detecting ABCB5 in ELISA. Suitable for Human.
Highlights
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| Species reactivity | Human | ||||
| Applications | ELISA | ||||
| Host species | Human | ||||
| Clonality | Monoclonal | ||||
| Isotype | IgG1, kappa | ||||
| Clone ID | SAA3086 | ||||
| Target | ABCB5, ABCB5 P-gp, ATP-binding cassette sub-family B member 5, EC:7.6.2.2, P-glycoprotein ABCB5 | ||||
| Endotoxin level | < 10 EU/mg as determined by LAL method. | ||||
| Purity | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Accession | Q2M3G0 | ||||
| Form | Liquid | ||||
| Storage buffer | 0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. | ||||
| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Background | ATP-binding cassette sub-family B member 5 (ABCB5) is a ~138 kDa protein. Energy-dependent efflux transporter responsible for decreased drug accumulation in multidrug-resistant cells. Specifically present in limbal stem cells, where it plays a key role in corneal development and repair. 1. Frank, NY. et al. (2003) The Journal of biological chemistry 278, 47156-65. PMID: 12960149 2. Huang, Y. et al. (2004) Cancer research 64, 4294-301. PMID: 15205344 3. Frank, NY. et al. (2005) Cancer research 65, 4320-33. PMID: 15899824 4. Kawanobe, T. et al. (2012) Biochemical and biophysical research communications 418, 736-41. PMID: 22306008 | ||||
| Note | For research use only. |




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