Anti-CD155/PVR Polyclonal Antibody (HB135014)

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Overview
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Datasheet

Overview

Catalog No.

HB135014

Description

Anti-CD155/PVR Polyclonal Antibody (HB135014) is a rabbit polyclonal antibody detecting CD155 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human, Chlorocebus aethiops

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CD155/PVR (Trp21-Asn343).

Target

Nectin-like protein 5, Poliovirus receptor, CD155, PVR, PVS, NECL-5

Purification

Purified by antigen affinity column.

Accession

P15151

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Poliovirus receptor (CD155/PVR) is a ~45 kDa protein. Mediates NK cell adhesion and triggers NK cell effector functions. Binds two different NK cell receptors: CD96 and CD226. These interactions accumulates at the cell-cell contact site, leading to the formation of a mature immunological synapse between NK cell and target cell. This may trigger adhesion and secretion of lytic granules and IFN-gamma and activate cytotoxicity of activated NK cells. May also promote NK cell-target cell modular exchange, and PVR transfer to the NK cell.

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-PVR polyclonal antibody at 1μg/ml on various samples.
Lane 1: Hela cell lysate
Lane 2: A549 cell lysate
Lane 3: HUVEC cell lysate
Lane 4: LO2 cell lysate