Anti-HSPA1L Polyclonal Antibody (HW649014)

Name: Anti-HSPA1L Polyclonal Antibody
Brand: abinScience
SKU: HW649014
Price: 96 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HW649014

Description

Anti-HSPA1L Polyclonal Antibody (HW649014) is a rabbit polyclonal antibody detecting HSPA1L in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Bos mutus grunniens.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human HSPA1L (Met1-Asp641).

Target

HSP70-Hom, Heat shock 70 kDa protein 1L, Heat shock 70 kDa protein 1-like, HSPA1L, Heat shock 70 kDa protein 1-Hom

Purification

Purified by antigen affinity column.

Accession

P34931

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Heat shock 70 kDa protein 1-like (HSPA1L) is a ~70 kDa protein. Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis and ADP release, mediated by co-chaperones. The affinity for polypeptides is regulated by its nucleotide bound state. In the ATP-bound form, it has a low affinity for substrate proteins.

1. Radons, J. (2016) Cell stress & chaperones 21, 379-404. PMID: 26865365

2. Hasson, SA. et al. (2013) Nature 504, 291-5. PMID: 24270810

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-HSPA1L polyclonal antibody at 1μg/ml on various samples.
Lane 1: PC12 cell lysate
Lane 2: HepG2 cell lysate
Lane 3: Human plasma lysate
Lane 4: Mouse spleen lysate
Lane 5: Mouse liver lysate
Lane 6: Mouse kidney lysate
Lane 7: Mouse lung lysate
Lane 8: Rat spleen lysate
Lane 9: Rat liver lysate
Lane 10: Rat kidney lysate

References

Datasheet

Anti-HSPA1L Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-HSPA1L Polyclonal Antibody (HW649014)

Overview

Images

References

Datasheet

SDS

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