Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application
Dilution
ELISA
1:5000-1:20000
IHC
1:50-1:500
WB
1:500-1:2000
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names
SNAP25, Super protein, SUP, Synaptosomal-associated protein 25, SNAP, SNAP-25, Synaptosomal-associated 25 kDa protein
Background
Synaptosomal-associated protein 25 (SNAP25) is a ~23 kDa protein. t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells.
1. Blasi, J. et al. (1993) Nature 365, 160-3. PMID: 8103915
2. Schiavo, G. et al. (1993) FEBS letters 335, 99-103. PMID: 8243676
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