Anti-Human CDH1/CDH11 Antibody (23C6), FITC (HY460317)

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Overview

Catalog No.	HY460317
Description	Anti-Human CDH1/CDH11 Antibody (23C6), FITC (HY460317) is a mouse monoclonal antibody detecting CDH11. Suitable for Human.
Species reactivity	Human
Applications	FCM
Host species	Mouse
Isotype	IgG2a, kappa
Clone ID	23C6
Conjugation	FITC
Clonality	Monoclonal
Target	CAM 120/80, CD324, CDH1, CDHE, Cadherin-1, E-Cad/CTF1, E-Cad/CTF2, E-Cad/CTF3, E-cadherin, Epithelial cadherin, UVO, Uvomorulin, CDH11, Cadherin-11, OB-cadherin, OSF-4, Osteoblast cadherin
Endotoxin level	Please contact with the lab for this information.
Accession	P12830, P55287
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	Cadherin-1 (CDH1/CDH11) is a ~97 kDa protein. Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Promotes organization of radial actin fiber structure and cellular response to contractile forces, via its interaction with AMOTL2 which facilitates anchoring of radial actin fibers to CDH1 junction complexes at the cell membrane. Plays a role in the early stages of desmosome cell-cell junction formation via facilitating the recruitment of DSG2 and DSP to desmosome plaques. 1. Meigs, TE. et al. (2002) The Journal of biological chemistry 277, 24594-600. PMID: 11976333 2. Shafraz, O. et al. (2018) eLife 7. PMID: 29999492
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Datasheet

Anti-Human CDH1/CDH11 Antibody (23C6), FITC.pdf

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Anti-Human CDH1/CDH11 Antibody (23C6), FITC (HY460317)

Overview

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