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Anti-Human BCMA/TNFRSF17 Recombinant Antibody (SAA0086) (HX959107)

Anti-Human BCMA/TNFRSF17 Recombinant Antibody (SAA0086)
Anti-Human BCMA/TNFRSF17 Recombinant Antibody (SAA0086)
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Overview
Catalog No.HX959107
Species reactivityHuman
ApplicationsFCM
Host speciesHuman
ClonalityMonoclonal
IsotypeIgG1, kappa
Clone IDSAA0086
Tested applications FCM
Target B-cell maturation protein, BCM, BCMA, CD269, TNFRSF17, Tumor necrosis factor receptor superfamily member 17
Endotoxin level < 10 EU/mg
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q02223
Form Liquid
Storage buffer 0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Tumor necrosis factor receptor superfamily member 17 (CD269/BCMA) is a ~20 kDa protein. Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK. CD269 is the therapeutic target of teclistamab (Tecvayli).

Note For research use only.
Images
  • Anti-Human BCMA/TNFRSF17 Recombinant Antibody (SAA0086)

    Flow Cytometry

    Flow-cytometry using anti-human CD269 antibody.CD269 Transfected CHO cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human CD269 antibody monoclonal antibody (Catalog # HX959107 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-human antibody (Catalog # HF690414) and cells analysed on a NovoCyte Flow Cytometer.

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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