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Anti-Human CD273/PD-L2/PDCD1LG2 Antibody (24F.10C12) (HV809107)

Anti-Human CD273/PD-L2/PDCD1LG2 Antibody (24F.10C12)
Anti-Human CD273/PD-L2/PDCD1LG2 Antibody (24F.10C12)
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Overview
Catalog No.HV809107
Description
Anti-Human CD273/PD-L2/PDCD1LG2 Antibody (24F.10C12) [24F.10C12] (HV809107) is a mouse monoclonal antibody detecting PD-L2 in FCM. Suitable for Human.
Highlights
  • Flow Cytometry — Validated for flow cytometry applications.
Species reactivityHuman
ApplicationsFCM
Host speciesMouse
IsotypeIgG1, kappa
Clone ID24F.10C12
Clonality Monoclonal
Target PDCD1 ligand 2, B7-DC, PD-L2, PDCD1LG2, PDCD1L2, PDL2, Butyrophilin B7-DC, Programmed death ligand 2, Programmed cell death 1 ligand 2, CD273, B7DC, PD-1 ligand 2
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q9BQ51
Form Liquid
Storage buffer 0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

Programmed cell death 1 ligand 2 (CD273/PD-L2) is a ~30 kDa protein. Plays a critical role in induction and maintenance of immune tolerance to self. Acts as a ligand for the inhibitory receptor PDCD1/PD-1, inhibiting T-cell proliferation by blocking cell cycle progression and cytokine production.

1. Latchman, Y. et al. (2001) Nature immunology 2, 261-8. PMID: 11224527
2. Brown, JA. et al. (2003) Journal of immunology (Baltimore, Md. : 1950) 170, 1257-66. PMID: 12538684
Note For research use only.
Images
  • Anti-Human CD273/PD-L2/PDCD1LG2 Antibody (24F.10C12)

    SDS-PAGE

    SDS-PAGE for Anti-Human CD273/PD-L2/PDCD1LG2 Antibody (24F.10C12)

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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