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Anti-Human CD40/TNFRSF5 Recombinant Antibody (SAA0014) (HB782207)

Anti-Human CD40/TNFRSF5 Recombinant Antibody (SAA0014)
Anti-Human CD40/TNFRSF5 Recombinant Antibody (SAA0014)
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Overview
Catalog No.HB782207
Species reactivityHuman
ApplicationsFCM
Host speciesHuman
ClonalityMonoclonal
IsotypeIgG2, kappa
Clone IDSAA0014
Target B-cell surface antigen CD40, Bp50, CD40, CD40L receptor, CDw40, TNFRSF5, Tumor necrosis factor receptor superfamily member 5
Endotoxin level < 10 EU/mg
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P25942
Form Liquid
Storage buffer 0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Tumor necrosis factor receptor superfamily member 5 (CD40/TNFRSF5) is a ~30 kDa protein. Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion.

1. Takada, YK. et al. (2019) Journal of immunology (Baltimore, Md. : 1950) 203, 1383-1391. PMID: 31331973
Note For research use only.
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  • Anti-Human CD40/TNFRSF5 Recombinant Antibody (SAA0014)

    Bioactivity

    SEC-HPLC detection for Anti-Human CD40/TNFRSF5 Antibody (ABS1911).

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
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Stock Solution
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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