Anti-Human CD95/FAS Antibody (SAA0040) (HB873107)

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Overview

Catalog No.	HB873107
Description	Anti-Human CD95/FAS Antibody (SAA0040) [SAA0040] (HB873107) is a human monoclonal antibody detecting CD95 in FCM. Suitable for Human. Highlights ●Flow Cytometry — Validated for flow cytometry applications.
Species reactivity	Human
Applications	FCM
Host species	Human
Isotype	IgG1, kappa
Clone ID	SAA0040
Clonality	Monoclonal
Target	APT1, TNFRSF6, FAS1, FASLG receptor, CD95, Apo-1 antigen, Tumor necrosis factor receptor superfamily member 6, FAS, Apoptosis-mediating surface antigen FAS
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P25445
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	Tumor necrosis factor receptor superfamily member 6 (CD95/FAS) is a ~37 kDa protein. Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase CASP8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs CASP8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).
Note	For research use only.

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Bioactivity

Detects Human CD95/FAS in indirect ELISAs.

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Datasheet

Anti-Human CD95/FAS Antibody (SAA0040).pdf

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Anti-Human CD95/FAS Antibody (SAA0040) (HB873107)

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