Anti-Mouse CD40/TNFRSF5 Antibody (FGK45) (MB782107)

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Overview

Catalog No.	MB782107
Description	Anti-Mouse CD40/TNFRSF5 Antibody (FGK45) [FGK45] (MB782107) is a rat monoclonal antibody detecting TNFRSF5 in in vivo NK cell depletion, FCMin vivo CD40 activation, in vitro B cell stimulation/activation. Suitable for Mouse. Highlights ●Multi-Application — Validated across multiple applications. ●Flow Cytometry — Validated for flow cytometry applications.
Species reactivity	Mouse
Applications	in vivo NK cell depletion, FCMin vivo CD40 activation, in vitro B cell stimulation/activation
Host species	Rat
Isotype	IgG2a, kappa
Clone ID	FGK45
Clonality	Monoclonal
Target	Tumor necrosis factor receptor superfamily member 5, B-cell surface antigen CD40, Bp50, CD40L receptor, TNFRSF5, CDw40, CD40
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P27512
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	Tumor necrosis factor receptor superfamily member 5 (CD40/TNFRSF5) is a ~32 kDa protein. Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion. 1. Eliopoulos, AG. et al. (2003) The EMBO journal 22, 3855-64. PMID: 12881420
Note	For research use only.

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Bioactivity

Detects CD40/TNFRSF5 in indirect ELISAs.

References

Datasheet

Anti-Mouse CD40/TNFRSF5 Antibody (FGK45).pdf

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Anti-Mouse CD40/TNFRSF5 Antibody (FGK45) (MB782107)

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