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Anti-Mouse CD230 Antibody (POM1) (MY392307)

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Anti-Mouse CD230 Antibody (POM1)

Anti-Mouse CD230 Antibody (POM1)

Anti-Mouse CD230 Antibody (POM1)

Anti-Mouse CD230 Antibody (POM1)

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Datasheet

Overview

Catalog No.	MY392307
Description	Anti-Mouse CD230 Antibody (POM1) [POM1] (MY392307) is a mouse monoclonal antibody detecting CD230 in ELISA, FCM. Suitable for Human, Mouse, Bovine, and Hamster. Highlights ●Flow Cytometry — Validated for flow cytometry applications. ●Multi-Species — Cross-reactive for translational research.
Species reactivity	Human, Mouse, Bovine, Hamster
Applications	ELISA, FCM
Host species	Mouse
Isotype	IgG2a, kappa
Clone ID	POM1
Clonality	Monoclonal
Target	Major prion protein, PrP, PrP27-30, PrP33-35C, CD230, Prnp, Prn-p
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P04925
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	Major prion protein (CD230/PRNP) is a ~27 kDa protein. Its primary physiological function is unclear. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May promote myelin homeostasis through acting as an agonist for ADGRG6 receptor. May play a role in iron uptake and iron homeostasis. 1. Mani, K. et al. (2003) The Journal of biological chemistry 278, 38956-65. PMID: 12732622 2. Steele, AD. et al. (2006) Proceedings of the National Academy of Sciences of the United States of America 103, 3416-21. PMID: 16492732 3. Laurén, J. et al. (2009) Nature 457, 1128-32. PMID: 19242475 4. Singh, A. et al. (2009) PloS one 4, e6115. PMID: 19568430
Note	For research use only.

Images

Bioactivity

Detects Human CD230/PRNP in indirect ELISAs.
Western blot

Western blot analysis was performed using anti-CD230/PRNP monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human CD230/PRNP (Catalog No: HY392011)
Lane 2: negative control

References

Datasheet

Anti-Mouse CD230 Antibody (POM1).pdf

Formula

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Anti-Mouse CD230 Antibody (POM1)