Anti-Human IL28B/IL28C/IFNL3 Recombinant Antibody (SAA0394) (HV083107)

Name: Anti-Human IL28B/IL28C/IFNL3 Recombinant Antibody (SAA0394)
Brand: abinScience
SKU: HV083107
Price: 196 USD
Availability: InStock

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Overview

Catalog No.	HV083107
Species reactivity	Human
Applications	ELISA, FCM
Host species	Mouse
Isotype	IgG2a, kappa
Clone ID	SAA0394
Clonality	Monoclonal
Target	IFNL3, IL28B, Interferon lambda-3, IL28C, IFN-lambda-3, Interleukin-28B, Interleukin-28C, Cytokine Zcyto22, IL-28B, ZCYTO22, IL-28C
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q8IZI9
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.09% Sodium azide. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	Interferon lambda-3 (IL28B/IL28C) is a ~21 kDa protein. Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense.
Note	For research use only.

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SDS-PAGE for Anti-Human IL28B/IL28C/IFNL3 Antibody (SAA0394)

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Datasheet

Anti-Human IL28B/IL28C/IFNL3 Recombinant Antibody (SAA0394).pdf

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Anti-Human IL28B/IL28C/IFNL3 Recombinant Antibody (SAA0394) (HV083107)

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