Anti-Human CLDN4/Claudin-4 Recombinant Antibody (SAA0509) (HT305107)

Name: Anti-Human CLDN4/Claudin-4 Recombinant Antibody (SAA0509)
Brand: abinScience
SKU: HT305107
Price: 191 USD
Availability: InStock

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Overview

Catalog No.	HT305107
Species reactivity	Human
Applications	ELISA, FCM, WB
Host species	Mouse
Isotype	IgG2a, kappa
Clone ID	SAA0509
Clonality	Monoclonal
Target	CPER, CLDN4, Williams-Beuren syndrome chromosomal region 8 protein, CPE-R, CPE-receptor, WBSCR8, Claudin 4, Clostridium perfringens enterotoxin receptor, CPETR1
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	O14493
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.09% Sodium azide. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	Claudin-4 (CLDN4) is a ~22 kDa protein. Can associate with other claudins to regulate tight junction structural and functional strand dynamics. May coassemble with CLDN8 into tight junction strands containing anion-selective channels that convey paracellular chloride permeability in renal collecting ducts. May integrate into CLDN3 strands to modulate localized tight junction barrier properties. May disrupt strand assembly of channel-forming CLDN2 and CLDN15 and inhibit cation conductance. Cannot form tight junction strands on its own. 1. Shashikanth, N. et al. (2022) Nature communications 13, 3780. PMID: 35773259 2. Gonschior, H. et al. (2022) Nature communications 13, 4985. PMID: 36008380
Note	For research use only.

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Anti-Human CLDN4/Claudin-4 Recombinant Antibody (SAA0509).pdf

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Anti-Human CLDN4/Claudin-4 Recombinant Antibody (SAA0509) (HT305107)

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