Anti-Human Fc gamma RIIIA/CD16a7a/DDR1 Recombinant Antibody (SAA0826) (HC282307)

Name: Anti-Human Fc gamma RIIIA/CD16a7a/DDR1 Recombinant Antibody (SAA0826)
Brand: abinScience
SKU: HC282307
Price: 191 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.	HC282307
Species reactivity	Human
Applications	ELISA, FCM
Host species	Mouse
Isotype	IgG1, kappa
Clone ID	SAA0826
Clonality	Monoclonal
Target	Protein-tyrosine kinase RTK-6, Protein-tyrosine kinase 3A, NTRK4, EDDR1, CAK, Tyrosine kinase DDR, Mammary carcinoma kinase 10, TRKE, Epithelial discoidin domain-containing receptor 1, CD167a, TRK E, Epithelial discoidin domain receptor 1, HGK2, CD167 antigen-like family member A, NEP, MCK-10, Tyrosine-protein kinase CAK, PTK3A, DDR1, Discoidin receptor tyrosine kinase, RTK6, Cell adhesion kinase
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q08345
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.09% Sodium azide. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	Epithelial discoidin domain-containing receptor 1 (CD167a/DDR1) is a ~101 kDa protein. Tyrosine kinase that functions as a cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing. Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing.
Note	For research use only.

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Bioactivity

Detects CD167a/DDR1 in indirect ELISAs.
Flow Cytometry

Flow-cytometry using anti-human CD167a antibody.CD167a Transfected CHO cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human CD167a antibody monoclonal antibody (Catalog # HC282307 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # MF690414) and cells analysed on a NovoCyte Flow Cytometer.