

| Catalog No. | MB873117 |
|---|---|
| Description |
Anti-Mouse CD95/FAS Antibody (HFE7A), FITC [HFE7A] (MB873117) is a rat monoclonal antibody detecting CD95 in ELISA, FCM, WB. Suitable for Human and Mouse.
Highlights
|
| Species reactivity | Human, Mouse |
| Applications | ELISA, FCM, WB |
| Host species | Rat |
| Isotype | IgG1, kappa |
| Clone ID | HFE7A |
| Conjugation | FITC |
| Clonality | Monoclonal |
| Target | Tumor necrosis factor receptor superfamily member 6, Apo-1 antigen, Apoptosis-mediating surface antigen FAS, FASLG receptor, CD95, Fas, Apt1, Tnfrsf6 |
| Endotoxin level | Please contact with the lab for this information. |
| Accession | P25446 |
| Form | Liquid |
| Storage buffer | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| Background | Tumor necrosis factor receptor superfamily member 6 (CD95/FAS) is a ~37 kDa protein. Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase CASP8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs CASP8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. |
| Note | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |




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