Anti-Human CLDN4/Claudin-4 Recombinant Antibody (SAA0509), APC (HT305137)

Name: Anti-Human CLDN4/Claudin-4 Recombinant Antibody (SAA0509), APC
Brand: abinScience
SKU: HT305137
Price: 290 USD
Availability: InStock

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Overview

Catalog No.	HT305137
Species reactivity	Human
Applications	ELISA, FCM, WB
Host species	Mouse
Isotype	IgG2a, kappa
Clone ID	SAA0509
Conjugation	APC
Clonality	Monoclonal
Target	CPER, CLDN4, Williams-Beuren syndrome chromosomal region 8 protein, CPE-R, CPE-receptor, WBSCR8, Claudin-4, Clostridium perfringens enterotoxin receptor, CPETR1
Endotoxin level	Please contact with the lab for this information.
Associated products	Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173), APC
Accession	O14493
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	Claudin-4 (CLDN4) is a ~22 kDa protein. Can associate with other claudins to regulate tight junction structural and functional strand dynamics. May coassemble with CLDN8 into tight junction strands containing anion-selective channels that convey paracellular chloride permeability in renal collecting ducts. May integrate into CLDN3 strands to modulate localized tight junction barrier properties. May disrupt strand assembly of channel-forming CLDN2 and CLDN15 and inhibit cation conductance. Cannot form tight junction strands on its own. 1. Shashikanth, N. et al. (2022) Nature communications 13, 3780. PMID: 35773259 2. Gonschior, H. et al. (2022) Nature communications 13, 4985. PMID: 36008380
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Anti-Human CLDN4/Claudin-4 Recombinant Antibody (SAA0509), APC.pdf

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Anti-Human CLDN4/Claudin-4 Recombinant Antibody (SAA0509), APC (HT305137)

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