

| Catalog No. | MY392347 |
|---|---|
| Description |
Anti-Mouse CD230 Antibody (POM1), PerCP [POM1] (MY392347) is a mouse monoclonal antibody detecting CD230 in ELISA, FCM. Suitable for Human, Mouse, Bovine, and Hamster.
Highlights
|
| Species reactivity | Human, Mouse, Bovine, Hamster |
| Applications | ELISA, FCM |
| Host species | Mouse |
| Isotype | IgG2a, kappa |
| Clone ID | POM1 |
| Conjugation | PerCP |
| Clonality | Monoclonal |
| Target | Major prion protein, PrP, PrP27-30, PrP33-35C, CD230, Prnp, Prn-p |
| Endotoxin level | Please contact with the lab for this information. |
| Accession | P04925 |
| Form | Liquid |
| Storage buffer | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| Background | Major prion protein (CD230/PRNP) is a ~27 kDa protein. Its primary physiological function is unclear. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May promote myelin homeostasis through acting as an agonist for ADGRG6 receptor. May play a role in iron uptake and iron homeostasis. 1. Mani, K. et al. (2003) The Journal of biological chemistry 278, 38956-65. PMID: 12732622 2. Steele, AD. et al. (2006) Proceedings of the National Academy of Sciences of the United States of America 103, 3416-21. PMID: 16492732 3. Laurén, J. et al. (2009) Nature 457, 1128-32. PMID: 19242475 4. Singh, A. et al. (2009) PloS one 4, e6115. PMID: 19568430 |
| Note | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |




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