Anti-Mouse CD45/PTPRC Antibody (SAA0570), PerCP (MY195147)

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Overview

Catalog No.	MY195147
Description	Anti-Mouse CD45/PTPRC Antibody (SAA0570), PerCP [SAA0570] (MY195147) is a mouse monoclonal antibody detecting PTPRC in FCM. Suitable for Mouse. Highlights ●Flow Cytometry — Validated for flow cytometry applications. ●Fluorescent Label — Direct conjugate for streamlined workflows.
Species reactivity	Mouse
Applications	FCM
Host species	Mouse
Isotype	VHH, mFc (IgG2a)
Clone ID	SAA0570
Conjugation	PerCP
Clonality	Monoclonal
Target	T200, Leukocyte common antigen, CD45, L-CA, Receptor-type tyrosine-protein phosphatase C, PTPRC
Endotoxin level	Please contact with the lab for this information.
Accession	P06800
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	Receptor-type tyrosine-protein phosphatase C (CD45/PTPRC) is a ~144 kDa protein. Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity.
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Anti-Mouse CD45/PTPRC Antibody (SAA0570), PerCP.pdf

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Anti-Mouse CD45/PTPRC Antibody (SAA0570), PerCP (MY195147)

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