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Anti-Human EPOR Antibody (ABT-007), PerCP (HB152147)

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Overview

Catalog No.	HB152147
Description	Anti-Human EPOR Antibody (ABT-007), PerCP [ABT-007] (HB152147) is a mouse monoclonal antibody detecting EPOR in FCM. Suitable for Human. Highlights ●Flow Cytometry — Validated for flow cytometry applications. ●Fluorescent Label — Direct conjugate for streamlined workflows.
Species reactivity	Human
Applications	FCM
Host species	Mouse
Isotype	IgG1, kappa
Clone ID	ABT-007
Conjugation	PerCP
Clonality	Monoclonal
Target	EPOR, Erythropoietin receptor, EPO-R
Endotoxin level	Please contact with the lab for this information.
Accession	P19235
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	Erythropoietin receptor (EPOR) is a ~55 kDa protein. Receptor for erythropoietin, which mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase. 1. Zhan, H. et al. (1999) Protein engineering 12, 505-13. PMID: 10388848 2. Winkelmann, JC. et al. (1990) Blood 76, 24-30. PMID: 2163695 3. Jones, SS. et al. (1990) Blood 76, 31-5. PMID: 2163696 4. Middleton, SA. et al. (1996) The Journal of biological chemistry 271, 14045-54. PMID: 8662939 5. Syed, RS. et al. (1998) Nature 395, 511-6. PMID: 9774108 6. Kirito, K. et al. (2002) Blood 99, 102-10. PMID: 11756159
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Datasheet

Anti-Human EPOR Antibody (ABT-007), PerCP.pdf

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Anti-Human EPOR Antibody (ABT-007), PerCP