Anti-Mouse ROR1 Antibody (R11), PerCP (MX065147)

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Catalog No.	MX065147
Description	Anti-Mouse ROR1 Antibody (R11), PerCP [R11] (MX065147) is a mouse monoclonal antibody detecting ROR1 in ELISA, FCM. Suitable for Human and Mouse. Highlights ●Flow Cytometry — Validated for flow cytometry applications. ●Fluorescent Label — Direct conjugate for streamlined workflows.
Species reactivity	Human, Mouse
Applications	ELISA, FCM
Host species	Mouse
Isotype	IgG2a, kappa
Clone ID	R11
Conjugation	PerCP
Clonality	Monoclonal
Target	Neurotrophic tyrosine kinase, receptor-related 1, Inactive tyrosine-protein kinase transmembrane receptor ROR1, NTRKR1, ROR1
Endotoxin level	Please contact with the lab for this information.
Accession	Q9Z139
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	Inactive tyrosine-protein kinase transmembrane receptor ROR1 (NTRKR1) is a ~104 kDa protein. Has very low kinase activity in vitro and is unlikely to function as a tyrosine kinase in vivo. Receptor for ligand WNT5A which activate downstream NFkB signaling pathway and may result in the inhibition of WNT3A-mediated signaling. In inner ear, crucial for spiral ganglion neurons to innervate auditory hair cells. Via IGFBP5 ligand, forms a complex with ERBB2 to enhance CREB oncogenic signaling. 1. Diaz-Horta, O. et al. (2016) Proceedings of the National Academy of Sciences of the United States of America 113, 5993-8. PMID: 27162350
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Anti-Mouse ROR1 Antibody (R11), PerCP.pdf

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Anti-Mouse ROR1 Antibody (R11), PerCP (MX065147)

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