Anti-Human P2RX4 Antibody (SAA0867), PerCP (HP943147)

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Overview

Catalog No.	HP943147
Description	Anti-Human P2RX4 Antibody (SAA0867), PerCP [SAA0867] (HP943147) is a mouse monoclonal antibody detecting P2RX4 in ELISA, FCM. Suitable for Human. Highlights ●Flow Cytometry — Validated for flow cytometry applications. ●Fluorescent Label — Direct conjugate for streamlined workflows.
Species reactivity	Human
Applications	ELISA, FCM
Host species	Mouse
Isotype	IgG2a, kappa
Clone ID	SAA0867
Conjugation	PerCP
Clonality	Monoclonal
Target	Purinergic receptor, P2RX4, P2X4, P2X purinoceptor 4, ATP receptor
Endotoxin level	Please contact with the lab for this information.
Accession	Q99571
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	P2X purinoceptor 4 (P2RX4) is a ~43 kDa protein. ATP-gated nonselective transmembrane cation channel permeable to potassium, sodium and calcium. CTP, but not GTP or UTP, functions as a weak affinity agonist for P2RX4. Activated by extracellularly released ATP, it plays multiple role in immunity and central nervous system physiology. Plays a key role in initial steps of T-cell activation and Ca(2+) microdomain formation. Also participates in basal T-cell activity without TCR/CD3 stimulation. 1. Garcia-Guzman, M. et al. (1997) Molecular pharmacology 51, 109-18. PMID: 9016352 2. Hamoudi, C. et al. (2022) Journal of immunology (Baltimore, Md. : 1950) 208, 1115-1127. PMID: 35165166
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Anti-Human P2RX4 Antibody (SAA0867), PerCP.pdf

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Anti-Human P2RX4 Antibody (SAA0867), PerCP (HP943147)

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