Anti-Human BDNF Antibody (SAA0471), PE (HB935127)

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Overview

Catalog No.	HB935127
Description	Anti-Human BDNF Antibody (SAA0471), PE [SAA0471] (HB935127) is a mouse monoclonal antibody detecting BDNF in ELISA, FCM. Suitable for Human. Highlights ●Flow Cytometry — Validated for flow cytometry applications.
Species reactivity	Human
Applications	ELISA, FCM
Host species	Mouse
Isotype	IgG2a, lambda
Clone ID	SAA0471
Conjugation	PE
Clonality	Monoclonal
Target	ProBDNF, Abrineurin, Brain-derived neurotrophic factor, BDNF
Endotoxin level	Please contact with the lab for this information.
Accession	P23560
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	Neurotrophic factor BDNF precursor form is a ~27 kDa protein. Important signaling molecule that activates signaling cascades downstream of NTRK2. During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability. 1. Mowla, SJ. et al. (2001) The Journal of biological chemistry 276, 12660-6. PMID: 11152678
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Anti-Human BDNF Antibody (SAA0471), PE.pdf

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Anti-Human BDNF Antibody (SAA0471), PE (HB935127)

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