Human ErbB2/Her2 Antibody Pair Set (HY286908)

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Overview

Catalog No.	HY286908
Description	Human ErbB2/Her2 Antibody Pair Set (HY286908) is a capture: human, detection: human antibody detecting ErbB2/Her2 in ELISA. Suitable for Human. Highlights ●Detection: Biotin Conjugated — Ready for direct detection without secondary antibody.
Sensitivity	14.9 pg/mL
Range	78.1 - 5,000 pg/mL
Species reactivity	Human
Host species	Capture: Human, Detection: Human
Immunogen	ErbB2/Her2
Conjugation	Detection: Biotin
Tested applications	S-ELISA
Target	CD340, EC:2.7.10.1, ERBB2, HER2, MLN 19, MLN19, Metastatic lymph node gene 19 protein, NEU, NGL, Proto-oncogene Neu, Proto-oncogene c-ErbB-2, Receptor tyrosine-protein kinase erbB-2, Tyrosine kinase-type cell surface receptor HER2, p185erbB2
Specificity	ErbB2/Her2
Accession	P04626
Applications	ELISA
Form	Liquid
Storage buffer	Capture: 0.01M PBS pH 7.4; Detection: 0.01M PBS pH 7.4, 50% glycerol Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Assay type	Sandwich ELISA
Specifications	Reagents are sufficient for at least 1 x 96 well plates using recommended protocol.
Background	Receptor tyrosine-protein kinase erbB-2 (CD340/ERBB2) is a ~137 kDa protein. Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Regulates outgrowth and stabilization of peripheral microtubules (MTs). Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane. CD340 is the therapeutic target of trastuzumab (Herceptin) and trastuzumab deruxtecan (Enhertu).
Note	For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Standard Curve

Standard Curve of Human ErbB2/Her2 Antibody Pair Set

References

Datasheet

Human ErbB2/Her2 Antibody Pair Set.pdf

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Protocol

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

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